Dr. Dorothea Portius – Medical & Scientific Advisor
Selected References from Science and Industry
A curated overview of my work across scientific research, strategic consulting, and media contributions.
Collaborations with Innovative Brands
Media Contributions & Publications
MDR – Wie wir uns schön essen – mit Ernährungstherapeutin Dr. Dorothea Portius
MDR – Wissenswertes zur richtigen Ernährung in den Wechseljahren
Scientific Expertise
My research focuses on the complex interconnections between nutrition, metabolism, and health. I specialize in metabolic disorders such as obesity, diabetes, and cardiovascular disease, with particular attention to underlying mechanisms, including insulin signaling pathways and microbiome dynamics.
Through my work at leading research institutions in California — including the Salk Institute and Sanford Burnham Prebys Medical Discovery Institute — I gained extensive experience in biomedical basic research, with a strong focus on RNA metabolism and its role in metabolic disease.
Currently, within my projects at Martin Luther University Halle-Wittenberg, my research centers on vitamin D metabolism, the skin microbiome, and obesity-associated metabolic alterations. In addition, as Head of the Research Team at DHBW Heilbronn (Baden-Wuerttemberg Cooperative State University), I focus on personalized nutrition strategies and their application to women’s health, particularly during menopause.
With an interdisciplinary approach and a strong emphasis on precision, my work aims to translate scientific findings into practical and sustainable solutions that contribute meaningfully to prevention and therapeutic strategies.
Scientific Publications
Peer-Reviewed Articles
Joisten, C., Hirschmüller, A., Bauer, P., …, Portius, D., et al. Sports Preparticipation Evaluation for Healthy Adults: A Consensus-Based German Guideline. Sports Med, 2025
Friedrichs K., Portius D., Personalisierte Ernährungsstrategien der Zukunft Innovative Ansätze für Frauen in der Menopause, Ernährung & Medizin 2025; 40(02): 78-84
Willimsky S., Portius D., Ernährungstherapeutische Ansätze bei Anorexia nervosa mit Schwerpunkt auf pflanzlicher Ernährung; Ernährung & Medizin, Thieme, 2025
Kevekordes M.C., Portius D.; Herausforderungen in der Versorgung und innovative Ansätze durch digitale Buddy-Programme- ein Fallbeispiel; Ernährung & Medizin, Thieme, 2025
Portius, D. Beyond Limits: The Fusion of Nature and Technology in Achieving Optimal Health—The Truth of Biohacking. In: Plugmann, P., Portius, D. (eds) Innovations in Healthcare and Outcome Measurement. Springer, 2025
Gjorgjieva M, Calo N, Sobolewski C, Portius D, Pitetti JL ,Berthou F, Ay AS, Peyrou M, Bourgoin L, Maeder C, Fournier M, Correia de Sousa M, Delangre E, Vinet L, Montet X, Sempoux C, Nef S, Foti M; Hepatic IR and IGF1R signaling govern distinct metabolic and carcinogenic processes upon PTEN deficiency in the liver., JHEP Reports, 2024
Schochow M., Schneeberg S., Portius D., Wick K., Trummer A., Ramminger S., Ernst A., Paridon H., Teach the teachers – Kommunikationstrainings für Lehrkräfte in den Gesundheitsfachberufen, PADUA, hogrefe, 2024
Mannhardt, S.M. and Portius D, Ernährungstherapeutische Beratung komplex erkrankter Patienten. Pädagogische Königsdisziplin zwischen Ernährungswissenschaft, Ernährungsmedizin und Psychologie, 2024. 39(01): p. 4-9.
Ramminger S, Zergiebel U, Berthold H, Zingel J, Wick K, Portius D. Interdisciplinary Screening and Treatment of Orthorexia – ISTO-Projekt – Erste Ergebnisse. Aktuel Ernahrungsmed 2023; 48(03): 18 – 19.
Zimmermann S, Rindlisbacher R, Ramminger S, Portius D. Einfluss eines pandemiebedingten Lockdowns auf das Körpergewicht von übergewichtigen und adipösen Kindern und Jugendlichen und den Erfolg eines Gewichtsreduktionsprogrammes. Aktuel Ernahrungsmed 2022; 47: 225-259.
Zergiebel U, Ramminger S, Traurig F, Heinze V., Unger H, Meusel S und Portius D. Gesünder Lebt sich Leichter; GeLLe Studie -Innovatives interdisziplinäres Programm zur gesundheitlichen Förderung sozial benachteiligter Personen in Deutschland. Aktuel Ernahrungsmed 2022; 47: 225-259.
Theiss E, Griebsch L, Lauer A, Janitschke D, …, Portius D, Grimm H, Hartmann T, Grimm M; Vitamin B12 increases phospholipid levels known to be reduced in Alzheimer´s disease and protects plasmalogens from H2O2-induced oxidative stress; Cells; 2022
Portius D; Anti-Inflammatory Dietary Approach to Prevent the Development and Progression of Non-Alcoholic Fatty Liver Diseases; Liver; 2022
Lauer A, Griebsch L, …, Valencak T, Portius D, Grimm H, Hartmann T and Grimm M; Impact of Vitamin D3 Deficiency on Phosphatidylcholine-/ Ethanolamine, Plasmalogen-, Lyso-Phosphatidylcholine-/ Ethanolamine, Carnitine- and Triacyl Glyceride-Homeostasis in Neuroblastoma Cells and Murine Brain; Bio-molecules 2021
Gjorgjieva M, Sobolewski C, Ay A-S, Correia de Sousa M, Portius D, Berthou F, Fournier M, Maeder C, Rantakari P, Zhang FP, Poutanen M, Picard D, Montet X, Nef S, Adibekian A and Foti M ; Genetic ablation of miR-22 fosters diet-induced obesity and NAFLD development.; J Pers Med.; 2020
Adam M, Heikelä H, Sobolewski C, Portius D, Mäki-Jouppila J, Mehmood A, Adhikari P, Esposito I, Elo LL, Zhang FP, Ruohonen ST, Strauss L, Foti M, Poutanen M.; Hydroxysteroid (17β) dehydrogenase 13 deficiency triggers hepatic steatosis and inflammation in mice.; FASEB J; 2018
Books
Portius D, Beyond Limits: The Fusion of Nature and Technology in Achieving Optimal Health—The Truth of Biohacking, In: Innovations in Healthcare and Outcome Measurement New Approaches for a Healthy Lifestyle; Springer; 2025
Dorothea Portius, Thomas Kartelmeyer; Die Kollagen-Formel; südwest Verlag; 2024
Portius D, Wish or Truth- Can digital interventions stop the obesity crisis?; Innovation in Life Sciences
The Digital Revolution, Springer, 2024
The Digital Revolution, Springer, 2024
Dorothea Portius, Isabel Lammert, Antonia Möse, Sophie Jurtz, Maximilian Blochberger-Claus, Friedrich Freiesleben; Mehr als Pizza; GRÄFE UND UNZER Verlag GmbH; 2022
Dorothea Portius; Ernährung, die uns schützt; GRÄFE UND UNZER Verlag GmbH; 2022
Portius D, Sobolewski C, and Foti M; MicroRNAs-dependent regulation of PPARs in metabolic diseases and cancers; PPAR Research; 2017
Sobolewski C, Calo N, Portius D, and Foti M; MicroRNAs in fatty liver disease; Seminars in Liver Disease 35(1):12-25 · February 2015
Fort A, Calo N, Portius D, Burgoin L, Peyrou M, and Foti M; Signaling Pathways in Liver Diseases, Third Edition, Edition: 3rd, Chapter: PI3K/PTEN signaling in liver diseases, Publisher: Wiley-Blackwell, Editors: Jean-Francois Dufour, Pierre-Alain Clavien (pp.287-313); October 2015
Edited Volumes
Portius D (Hrsg.); Ernährung & Psyche; Ernährung & Medizin 2024; 39(01): 1; DOI: 10.1055/a-2167-9522
Portius D. & Plugmann P.(Editors); Innovations in Healthcare and Outcome Measurement
New Approaches for a Healthy Lifestyle; Springer; 2025
New Approaches for a Healthy Lifestyle; Springer; 2025
Dr. Dorothea Portius - Medical & Scientific Advisor
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Dr. Dorothea Portius
Professional Associations & Memberships
My expertise and professional engagement are reinforced through active membership and advisory roles within respected professional organizations.
These networks allow me to remain closely aligned with current scientific developments and emerging trends in nutrition and health — ensuring that my work reflects the latest evidence and strategic insights.